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Anti-Human Complement C5 Reference Antibody (Greziprubart, RUO) (HF687186)

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Anti-Human Complement C5 Reference Antibody (Greziprubart, RUO)
Anti-Human Complement C5 Reference Antibody (Greziprubart, RUO)
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Especificación:
  • 100ug
  • 1mg
  • 5mg
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Vista general
Número de catálogoHF687186
Descripción
greziprubart (HF687186) is a research-grade recombinant antibody targeting C5a.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG1, Kappa
Especies Human
Objetivo C5a
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Número de acceso P01031
Forma Liquid
Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos2935485-57-5
Fondo

Complement C5 (C5a) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways.

1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586
2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047
3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019
4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279
5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456
6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human Complement C5 Reference Antibody (Greziprubart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade greziprubart

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human Complement C5 Reference Antibody (Greziprubart, RUO)

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