Anti-Human ErbB2/Her2 Reference Antibody (Hersintuzumab, RUO) (HY286706)

Name: Anti-Human ErbB2/Her2 Reference Antibody (Hersintuzumab, RUO)
Brand: abinScience
SKU: HY286706
Price: 370 USD
Availability: InStock

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概要

カタログ番号	HY286706
説明	Research Grade Hersintuzumab (HY286706) is a human monoclonal antibody detecting CD340/ERBB2/HER2 in ELISA, FACS, Functional assay. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	ELISA, FCM, Functional assay
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1 kappa
ターゲット	CD340, EC:2.7.10.1, ERBB2, HER2, MLN 19, MLN19, Metastatic lymph node gene 19 protein, NEU, NGL, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2
エンドトキシンレベル	< 10 EU/mg
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P04626
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.
注意事項	For research use only.
Isotype Control	Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)