









| Número de catálogo | HV599016 |
|---|---|
| Descripción |
Ianalumab (HV599016) is a research-grade recombinant antibody targeting CD268. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG1-kappa |
| Sistema de expresión | Mammalian cells |
| Objetivo | BR3, TNFRSF13C, BAFF receptor, BLyS receptor 3, Tumor necrosis factor receptor superfamily member 13C, CD268, B-cell-activating factor receptor, BAFFR, BAFF-R |
| Nivel de endotoxinas | < 10 EU/mg |
| Pureza | >95% purity as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | Q96RJ3 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | VAY-736, 1929549-92-7 |
| Fondo | Tumor necrosis factor receptor superfamily member 13C (CD268/TNFRSF13C) is a ~18 kDa protein. B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SEC-HPLC detection for Research Grade Ianalumab.

Detects CD268/TNFRSF13C in indirect ELISAs.

SDS-PAGE for Research Grade Ianalumab

Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and human BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.

Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and mouse BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.




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