Anti-Human BAFFR/TNFRSF13C Reference Antibody (Ianalumab, RUO) (HV599016)

Name: Anti-Human BAFFR/TNFRSF13C Reference Antibody (Ianalumab, RUO)
Brand: abinScience
SKU: HV599016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV599016
Description	Ianalumab (HV599016) is a research-grade recombinant antibody targeting CD268. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Cible	BR3, TNFRSF13C, BAFF receptor, BLyS receptor 3, Tumor necrosis factor receptor superfamily member 13C, CD268, B-cell-activating factor receptor, BAFFR, BAFF-R
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q96RJ3
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	VAY-736, 1929549-92-7
Contexte	Tumor necrosis factor receptor superfamily member 13C (CD268/TNFRSF13C) is a ~18 kDa protein. B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Ianalumab.
Bioactivity

Detects CD268/TNFRSF13C in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Ianalumab
Flow cytometry

Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and human BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and mouse BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.

Reférences

Fiche technique

Anti-Human BAFFR/TNFRSF13C Reference Antibody (Ianalumab, RUO).pdf

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