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| カタログ番号 | HV599016 |
|---|---|
| 説明 |
Ianalumab (HV599016) is a research-grade recombinant antibody targeting CD268. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1-kappa |
| 発現システム | Mammalian cells |
| ターゲット | BR3, TNFRSF13C, BAFF receptor, BLyS receptor 3, Tumor necrosis factor receptor superfamily member 13C, CD268, B-cell-activating factor receptor, BAFFR, BAFF-R |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q96RJ3 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | VAY-736, 1929549-92-7 |
| 背景 | Tumor necrosis factor receptor superfamily member 13C (CD268/TNFRSF13C) is a ~18 kDa protein. B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SEC-HPLC detection for Research Grade Ianalumab.
Detects CD268/TNFRSF13C in indirect ELISAs.
SDS-PAGE for Research Grade Ianalumab
Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and human BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.
Flow cytometry using Ianalumab-APC. Untransfected BAFFR-negative cells (blue histogram) and mouse BAFFR-stable transfected cells (yellow histogram) were incubated with APC-labeled Ianalumab (5 µg/ml) for 30 minutes at room temperature. After washing, cells were analyzed on a NovoCyte Flow Cytometer.
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