Anti-Human SLC1A5 Reference Antibody (Idactamab, RUO) (HS734016)

Name: Anti-Human SLC1A5 Reference Antibody (Idactamab, RUO)
Brand: abinScience
SKU: HS734016
Price: 176 USD
Availability: InStock

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100ug
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Обзор

Каталожный номер	HS734016
Описание	Idactamab (HS734016) is a research-grade recombinant antibody targeting Baboon M7 virus receptor. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-Kappa
Система экспрессии	Mammalian cells
Цель	Baboon M7 virus receptor, SLC1A5, Solute carrier family 1 member 5, ASCT2, RDR, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, ATB(0), Neutral amino acid transporter B(0), M7V1, RDRC
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q15758
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	INT-001, MEDI7247, 2245205-37-0
Фон	Neutral amino acid transporter B(0) (SLC1A5) is a ~56 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. The preferred substrate is the essential amino acid L-glutamine, a precursor for biosynthesis of proteins, nucleotides and amine sugars as well as an alternative fuel for mitochondrial oxidative phosphorylation. Exchanges L-glutamine with other neutral amino acids such as L-serine, L-threonine and L-asparagine in a bidirectional way. Provides L-glutamine to proliferating stem and activated cells driving the metabolic switch toward cell differentiation. 1. Dun, Y. et al. (2007) Experimental eye research 84, 191-9. PMID: 17094966 2. Pingitore, P. et al. (2013) Biochimica et biophysica acta 1828, 2238-46. PMID: 23756778 3. Scalise, M. et al. (2015) FEBS letters 589, 3617-23. PMID: 26492990 4. Garaeva, AA. et al. (2018) Nature structural & molecular biology 25, 515-521. PMID: 29872227 5. Mazza, T. et al. (2021) FEBS letters 595, 3030-3041. PMID: 34741534 6. Kekuda, R. et al. (1996) The Journal of biological chemistry 271, 18657-61. PMID: 8702519 7. Borowska, AM. et al. (2024) Nature communications 15, 6570. PMID: 39095408 8. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177 9. Oburoglu, L. et al. (2014) Cell stem cell 15, 169-84. PMID: 24953180
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)

Изображения

Bioactivity

SEC-HPLC detection for Research Grade Idactamab.
SDS-PAGE

SDS-PAGE for Research Grade Idactamab.

Ссылки

Даташит

Anti-Human SLC1A5 Reference Antibody (Idactamab, RUO).pdf

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Formula

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