Anti-Human CD79B Reference Antibody (Iladatuzumab, RUO) (HW431026)

Name: Anti-Human CD79B Reference Antibody (Iladatuzumab, RUO)
Brand: abinScience
SKU: HW431026
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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Referencias
Datasheet
SDS

Vista general

Número de catálogo	HW431026
Descripción	Iladatuzumab (HW431026) is a research-grade recombinant antibody targeting CD79B. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa
Sistema de expresión	Mammalian cells
Aplicaciones probadas	WB, FCM
Objetivo	B-cell-specific glycoprotein B29, CD79B, B-cell antigen receptor complex-associated protein beta chain, Ig-beta, B29, Immunoglobulin-associated B29 protein, IGB, CD79b
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P40259
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	DCDS0780A, MCDS0593A, RO7032005, 1906205-76-2
Fondo	B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~26 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy).
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Imágenes

Bioactivity

Detects CD79β/CD79B in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Iladatuzumab
Western blot

Western blot analysis was performed using anti-CD79β/CD79B monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD79β/CD79B (Catalog No: HW431011)
Flow cytometry

Flow-cytometry using APC anti-human CD79B antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD79B monoclonal antibody (Catalog HW431026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using PE anti-human CD79B antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD79B monoclonal antibody (Catalog HW431026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using FITC anti-human CD79B antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD79B monoclonal antibody (Catalog HW431026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.