Anti-Human CD79B Reference Antibody (Iladatuzumab, RUO) (HW431026)

Name: Anti-Human CD79B Reference Antibody (Iladatuzumab, RUO)
Brand: abinScience
SKU: HW431026
Price: 176 USD
Availability: InStock

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100ug
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Изображения
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Даташит
SDS

Обзор

Каталожный номер	HW431026
Описание	Iladatuzumab (HW431026) is a research-grade recombinant antibody targeting CD79B. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-kappa
Система экспрессии	Mammalian cells
Проверенные приложения	WB, FCM
Цель	B-cell-specific glycoprotein B29, CD79B, B-cell antigen receptor complex-associated protein beta chain, Ig-beta, B29, Immunoglobulin-associated B29 protein, IGB, CD79b
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P40259
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	DCDS0780A, MCDS0593A, RO7032005, 1906205-76-2
Фон	B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~26 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy).
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Anti-LASV GPC Recombinant Antibody (Fab 37.7) (VK453013)

Изображения

Bioactivity

Detects CD79β/CD79B in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Iladatuzumab
Western blot

Western blot analysis was performed using anti-CD79β/CD79B monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD79β/CD79B (Catalog No: HW431011)
Flow cytometry

Flow-cytometry using APC anti-human CD79B antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD79B monoclonal antibody (Catalog HW431026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using PE anti-human CD79B antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD79B monoclonal antibody (Catalog HW431026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using FITC anti-human CD79B antibody. Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD79B monoclonal antibody (Catalog HW431026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.