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Anti-Human CD6 Reference Antibody (Itolizumab, RUO)
Anti-Human CD6 Reference Antibody (Itolizumab, RUO)
Anti-Human CD6 Reference Antibody (Itolizumab, RUO)
Anti-Human CD6 Reference Antibody (Itolizumab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHB797016
Описание
Research Grade Itolizumab (HB797016) is a humanized monoclonal antibody detecting TP120 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-kappa
Система экспрессии Mammalian cells
Виды Human
Цель TP120, CD6, T12, T-cell differentiation antigen CD6
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P30203
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияT1h, 1116433-11-4
Фон

T-cell differentiation antigen CD6 (TP120,CD6,T12,T-cell differentiation antigen CD6) is a ~71 kDa protein. Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as a costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as a calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria.

1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703
2. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938
3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806
4. Hassan, NJ. et al. (2006) Molecular and cellular biology 26, 6727-38. PMID: 16914752
5. Roncagalli, R. et al. (2014) Nature immunology 15, 384-392. PMID: 24584089
6. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Изображения
  • Anti-Human CD6 Reference Antibody (Itolizumab, RUO)

    Bioactivity

    Detects CD6 in indirect ELISAs.

  • Anti-Human CD6 Reference Antibody (Itolizumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Itolizumab.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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