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Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO) (HY515016)

Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO)
Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO)
Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO)
Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO)
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  • 100ug
  • 1mg
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  • 概要

  • イメージ

  • 参考文献

  • データシート

  • SDS

概要
カタログ番号HY515016
説明
Research Grade Lacnotuzumab (HY515016) is a humanized monoclonal antibody detecting CSF1 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG1-kappa
発現システム Mammalian cells
種 Human
ターゲット CSF1, Macrophage colony-stimulating factor 1, CSF-1, Lanimostim, M-CSF, MCSF
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P09603
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名MCS-110, 1831128-32-5
背景

Macrophage colony-stimulating factor 1 (CSF1,Macrophage colony-stimulating factor 1,CSF-1,Lanimostim,M-CSF,MCSF) is a ~60 kDa protein. Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
イメージ
  • Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO)

    Bioactivity

    Detects Human CSF1/M-CSF in indirect ELISAs.

  • Anti-Human M-CSF Reference Antibody (Lacnotuzumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Lacnotuzumab.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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