Anti-Human Kallikrein/KLKB1 Reference Antibody (Lanadelumab, RUO) (HY547016)

Name: Anti-Human Kallikrein/KLKB1 Reference Antibody (Lanadelumab, RUO)
Brand: abinScience
SKU: HY547016
Price: 176 USD
Availability: InStock

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概要
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概要

カタログ番号	HY547016
説明	Lanadelumab (HY547016) is a research-grade recombinant antibody targeting Plasma prekallikrein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
発現システム	Mammalian cells
ターゲット	Plasma prekallikrein, KLK3, Fletcher factor, KLKB1, Kininogenin, Plasma kallikrein, PKK
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P03952
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	X124-G01, DX-2930, 1426055-14-2
背景	Plasma kallikrein (KLKB1/KLK3) is a ~71 kDa protein. Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)