Anti-Human Sortilin Reference Antibody (Latozinemab, RUO) (HV066016)

Name: Anti-Human Sortilin Reference Antibody (Latozinemab, RUO)
Brand: abinScience
SKU: HV066016
Price: 176 USD
Availability: InStock

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Vista general

Número de catálogo	HV066016
Descripción	Latozinemab (HV066016) is a research-grade recombinant antibody targeting Neurotensin receptor 3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-Kappa
Sistema de expresión	Mammalian cells
Objetivo	Neurotensin receptor 3, Gp95, Glycoprotein 95, Sortilin, 100 kDa NT receptor, NTR3, SORT1, NT3
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q99523
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	AL001, 2376132-27-1
Fondo	Sortilin (SORT1/Gp95) is a ~92 kDa protein. Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. Also required for protein transport from the Golgi apparatus to the endosomes. 1. Ni, X. et al. (2006) Traffic (Copenhagen, Denmark) 7, 889-902. PMID: 16787399
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 (LALAPG) Recombinant Isotype Control Antibody (HyHEL-10) (HP688307)

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Latozinemab

Referencias

Datasheet

Anti-Human Sortilin Reference Antibody (Latozinemab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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