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Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO) (VK515056)

Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO)
Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO)
Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO)
Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO)
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Aperçu
Numéro de catalogueVK515056
Description
Lesofavumab (VK515056) is a research-grade recombinant antibody targeting HA/Hemagglutinin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesInfluenza B virus
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
Cible HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès CAS: 1807960-57-1
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsRG6024, RG6024, MHAB5553A, RG70026, RO7045557, 1807960-57-1
Contexte

Hemagglutinin (HA) is a ~62 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Lesofavumab.

  • Anti-Influenza B virus HA/Hemagglutinin Reference Antibody (Lesofavumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Lesofavumab

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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