





| Numéro de catalogue | VK539036 |
|---|---|
| Description |
Libivirumab (VK539036) is a research-grade recombinant antibody targeting Large envelope protein. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactivité des espèces | Hepatitis B virus (HBV) |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| Système d'expression | Mammalian cells |
| Cible | Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S |
| Niveau d'endotoxines | < 10 EU/mg |
| Pureté | >95% purity as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P03142 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | 17.1.41, HepeX-B(combinationofexbivirumabandlibivirumab), 569658-79-3 |
| Contexte | Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Libivirumab.

Detects S/L-HBsAg/L glycoprotein in indirect ELISAs.

SDS-PAGE for Anti-HBsAg Reference Antibody (Libivirumab, RUO)




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