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Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO) (VK539036)

Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)
Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)
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Aperçu
Numéro de catalogueVK539036
Description
Libivirumab (VK539036) is a research-grade recombinant antibody targeting Large envelope protein. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHepatitis B virus (HBV)
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
Système d'expression Mammalian cells
Cible Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P03142
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs17.1.41, HepeX-B(combinationofexbivirumabandlibivirumab), 569658-79-3
Contexte

Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Libivirumab.

  • Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)

    Bioactivity

    Detects S/L-HBsAg/L glycoprotein in indirect ELISAs.

  • Anti-HBV HBsAg Reference Antibody (Libivirumab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-HBsAg Reference Antibody (Libivirumab, RUO)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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