Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO) (HW759016)

Name: Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
Brand: abinScience
SKU: HW759016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HW759016
Description	Lirilumab (HW759016) is a research-grade recombinant antibody targeting CD158. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG4-kappa
Système d'expression	Mammalian cells
Cible	CD158 antigen-like family member A, KIR2DL1, Killer cell immunoglobulin-like receptor 2DL1, Natural killer-associated transcript 1, NKAT-1, MHC class I NK cell receptor, CD158A, p58 natural killer cell receptor clones CL-42/47.11, CD158a, p58.1 MHC class-I-specific NK receptor, NKAT1, p58 NK receptor CL-42/47.11, p58 NK receptor CL-43, NKAT-6, NKAT6, MHC class I NK cell receptor, CD158 antigen-like family member B1, CD158b1, p58 natural killer cell receptor clone CL-43, Natural killer-associated transcript 6, CD158B1, KIR2DL2, Killer cell immunoglobulin-like receptor 2DL2, NKAT2b, KIR2DL3, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158 antigen-like family member B2, MHC class I NK cell receptor, KIR-023GB, Killer inhibitory receptor cl 2-3, p58 NK receptor CL-6, CD158b2, Killer cell immunoglobulin-like receptor 2DL3, Natural killer-associated transcript 2, CD158B2, KIRCL23, NKAT-2, NKAT2a, NKAT2
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P43626 & P43627 & P43628
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	BMS-986015, IPH2102, 1000676-41-4
Contexte	Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) Human IgG4 (S228P) Recombinant Isotype Control Antibody (HyHEL-10) (HP298307) Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

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SEC-HPLC

SEC-HPLC detection for Research Grade Lirilumab.
Bioactivity

Detects Human CD158b1/KIR2DL2 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Lirilumab.

Reférences

Fiche technique

Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO).pdf

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