Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO) (HF977036)

Name: Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO)
Brand: abinScience
SKU: HF977036
Price: 176 USD
Availability: InStock

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Vista general

Número de catálogo	HF977036
Descripción	Livmoniplimab (HF977036) is a research-grade recombinant antibody targeting Transforming growth factor beta-1 proprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG4-kappa
Objetivo	LAP, Latency-associated peptide, TGF-beta-1, TGFB, TGFB1, Transforming growth factor beta-1, Transforming growth factor beta-1 proprotein, D11S833E, GARP, Garpin, Glycoprotein A repetitions predominant, LRRC32, Leucine-rich repeat-containing protein 32, Transforming growth factor beta activator LRRC32
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P01137 & Q14392
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Bispecific, ABBV-151, ARGX-115, MHG-8, MHGARP-8, PR-17628442412004-88-5
Fondo	Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

Imágenes

Bioactivity

SEC-HPLC detection for Research Grade Livmoniplimab.

Referencias

Datasheet

Anti-Human TGF-beta 1 & LRRC32/GARP Bispecific Reference Antibody (Livmoniplimab, RUO).pdf

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Formula

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