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Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO) (HB112016)

Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)
Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)
Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)
Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)
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Aperçu
Numéro de catalogueHB112016
Description
Mavrilimumab (HB112016) is a research-grade recombinant antibody targeting CD116. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG4-lambda2
Système d'expression Mammalian cells
Cible CD116, CSF2R, GMR-alpha, CSF2RA, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, CSF2RY, GMCSFR-alpha, GM-CSF-R-alpha, CDw116
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P15509
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsCAM-3001, 1085337-57-0
Contexte

Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (CD116/CSF2RA) is a ~46 kDa protein. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107)
Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)
Images
  • Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)

    Bioactivity

    Detects CD116/CSF2RA in indirect ELISAs.

  • Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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