Anti-RABV Glycoprotein G Reference Antibody (Mazorelvimab, RUO) (VK632036)

Name: Anti-RABV Glycoprotein G Reference Antibody (Mazorelvimab, RUO)
Brand: abinScience
SKU: VK632036
Price: 326 USD
Availability: InStock

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Número de catálogo	VK632036
Descripción	Mazorelvimab (VK632036) is a research-grade recombinant antibody targeting G. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Rabies virus (RABV)
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
Sistema de expresión	Mammalian cells
Objetivo	G, Glycoprotein
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O92284, P08667
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CTB012, CTB-012, CTB012, SYN023, CAS: 2419087-89-9
Fondo	Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Nota	For research use only. Not suitable for clinical or therapeutic use.