

| Número de catálogo | HW564106 |
|---|---|
| Descripción |
mebarase alfa (HW564106) is a research-grade recombinant antibody targeting CD39.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | Functional assay |
| Clonalidad | Monoclonal |
| Isotipo | ATPDase |
| Sistema de expresión | Mammalian cells |
| Naturaleza | Recombinant |
| Objetivo | CD39/ENTPD1 |
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. |
| Pureza | >95% as determined by SDS-PAGE. |
| Número de acceso | P49961 |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | CAS: 2408855-55-8 |
| Fondo | Ectonucleoside triphosphate diphosphohydrolase 1 is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. 1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670 2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624 3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160 4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251 |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |




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