

| Numéro de catalogue | HW564106 |
|---|---|
| Description |
mebarase alfa (HW564106) is a research-grade recombinant antibody targeting CD39.
Highlights
|
| Reactivité des espèces | Human |
| Applications | Functional assay |
| Clonalité | Monoclonal |
| Isotype | ATPDase |
| Système d'expression | Mammalian cells |
| Nature | Recombinant |
| Cible | CD39/ENTPD1 |
| Niveau d'endotoxines | < 10 EU/mg as determined by LAL method. |
| Pureté | >95% as determined by SDS-PAGE. |
| Numéro d'accès | P49961 |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CAS: 2408855-55-8 |
| Contexte | Ectonucleoside triphosphate diphosphohydrolase 1 is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. 1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670 2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624 3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160 4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |




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