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| カタログ番号 | HW564106 |
|---|---|
| 説明 |
mebarase alfa (HW564106) is a research-grade recombinant antibody targeting CD39.
Highlights
|
| 種反応性 | Human |
| アプリケーション | Functional assay |
| クローン性 | Monoclonal |
| アイソタイプ | ATPDase |
| 発現システム | Mammalian cells |
| 性質 | Recombinant |
| ターゲット | CD39/ENTPD1 |
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. |
| 純度 | >95% as determined by SDS-PAGE. |
| アクセッション番号 | P49961 |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CAS: 2408855-55-8 |
| 背景 | Ectonucleoside triphosphate diphosphohydrolase 1 is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. 1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670 2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624 3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160 4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
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