Anti-Human IL-17C Reference Antibody (Mor106, RUO) (HV335026)

Name: Anti-Human IL-17C Reference Antibody (Mor106, RUO)
Brand: abinScience
SKU: HV335026
Price: 370 USD
Availability: InStock

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Especificación:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Número:

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Referencias
Datasheet
SDS

Vista general

Número de catálogo

HV335026

Descripción

MOR106 (HV335026) is a research-grade recombinant antibody targeting Cytokine CX2.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.

Reactividad de especies

Human

Aplicaciones

ELISA, FACS, Functional assay

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG1, kappa

Objetivo

Cytokine CX2, IL-17C, IL17C, Interleukin-17C

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9P0M4

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Interleukin-17C (IL17C) is a ~21 kDa protein. Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype.

Nota

For research use only.

Imágenes