Anti-Human IL-17C Reference Antibody (Mor106, RUO) (HV335026)

Name: Anti-Human IL-17C Reference Antibody (Mor106, RUO)
Brand: abinScience
SKU: HV335026
Price: 370 USD
Availability: InStock

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100ug
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概要
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参考文献
データシート
SDS

概要

カタログ番号

HV335026

説明

MOR106 (HV335026) is a research-grade recombinant antibody targeting Cytokine CX2.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.

種反応性

Human

アプリケーション

ELISA, FACS, Functional assay

宿主種

Human

クローン性

Monoclonal

アイソタイプ

IgG1, kappa

ターゲット

Cytokine CX2, IL-17C, IL17C, Interleukin-17C

エンドトキシンレベル

< 10 EU/mg

純度

>95% as determined by SDS-PAGE.

精製

Protein A/G purified from cell culture supernatant.

アクセッション番号

Q9P0M4

形態

Liquid

保存バッファー

0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:2000-1:20000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-17C (IL17C) is a ~21 kDa protein. Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype.

注意事項

For research use only.

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