



| カタログ番号 | HT009016 |
|---|---|
| 説明 |
Nadecnemab (HT009016) is a research-grade recombinant antibody targeting GFR-alpha-3. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG4-Kappa |
| 発現システム | Mammalian cells |
| ターゲット | GFR-alpha-3, GDNF receptor alpha-3, GDNF family receptor alpha-3, GDNFR-alpha-3, GFRA3 |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% purity as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | O60609 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | REGN5069, 2377679-19-9 |
| 背景 | GDNF family receptor alpha-3 (GFRA3) is a ~44 kDa protein. Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons. ARTN-binding leads to autophosphorylation and activation of the RET receptor. 1. Li, J. et al. (2019) eLife 8. PMID: 31535977 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107) |

SEC-HPLC detection for Research Grade Nadecnemab.

Detects GFRA3 in indirect ELISAs.




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