Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 & ROR1 & CD3 epsilon Reference Antibody (Nebratamig, RUO) (HC336146)

Name: Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 & ROR1 & CD3 epsilon Reference Antibody (Nebratamig, RUO)
Brand: abinScience
SKU: HC336146
Price: 224 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC336146

Description

Nebratamig (HC336146) is a research-grade recombinant antibody targeting CD137. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactivité des espèces

Human

Applications

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

scFv-G1-scFv-scFv_L-kappa

Applications testées

Cible

4-1BB ligand receptor, CD137, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, Tumor necrosis factor receptor superfamily member 9, B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, Neurotrophic tyrosine kinase, receptor-related 1, ROR1, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q07011 & Q9NZQ7 & Q01973 & P07766

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

2694723-68-5

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SDS-PAGE

SDS-PAGE for Research Grade Nebratamig.
Bioactivity

Detects recombinant ROR1 (Catalog No: HX065022) in indirect ELISA.
Bioactivity

Detects recombinant ROR1 (Catalog No: HX065011) in indirect ELISA.
Bioactivity

Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Bioactivity

Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human PDL1 (Catalog No: HV974011)
Lane 2: recombinant human NCR1 (Catalog No: HY057021)
Western blot

Lane 1: recombinant human ROR1 (Catalog No: HX065011)
Lane 2: recombinant human ROR1/NTRKR1 (Catalog No: HX065022)
Immunofluorescence

Immunofluorescence staining of HDLM2 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.
Immunofluorescence

Immunofluorescence staining of HEK293T cells overexpressing PD-L1 with Human monoclonal antibody (20ug/ml, overnight at 4°C), followed by Alexa Fluor-488-conjugated secondary antibody (6.5ug/ml, 50minutes at room temperature). The target protein was detected in the cell membrane.

Reférences

Fiche technique

Anti-Human 4-1BB/TNFRSF9/CD137 & PD-L1 & ROR1 & CD3 epsilon Reference Antibody (Nebratamig, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Working Solution

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