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Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO) (CV121016)

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Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO)
Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO)
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Vista general
Número de catálogoCV121016
Descripción
Nolavetbart (CV121016) is a research-grade recombinant antibody targeting IL31RA. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesCanine
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedCanine
ClonalidadMonoclonal
IsotipoIgG2-kappa
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo IL31RA
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso A0A8I3Q391
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos2750248-93-0
Fondo

Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449
2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285
3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700
4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637
5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Nolavetbart

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO)

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