Anti-Human Fibronectin&TNF-alpha Reference Antibody (Onfekafusp Alfa, RUO) (HP900016)

Name: Anti-Human Fibronectin&TNF-alpha Reference Antibody (Onfekafusp Alfa, RUO)
Brand: abinScience
SKU: HP900016
Price: 424 USD
Availability: InStock

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Número de catálogo	HP900016
Descripción	Onfekafusp Alfa (HP900016) is a research-grade recombinant antibody targeting EDB. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	[scFv-heavy-kappa-TNF(tumornecrosisfactor(TNF)superfamilymember2, TNFSF2, TNF-alpha, TNFA)]-trimer
ID de clon	Onfekafusp Alfa
Sistema de expresión	Mammalian cells
Naturaleza	Recombinant
Objetivo	EDB, EDB-FN
Nivel de endotoxinas	< 10 EU/mg as determined by LAL method.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P02751-7
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	L19TNF, L19TNF-alpha, 1957239-88-1
Fondo	Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research. • EDB-FN targeted probes for the surgical navigation, radionuclide imaging, and therapy of thyroid cancer., PMID:36807768 • EDB-FN Targeted Peptide-Drug Conjugates for Use against Prostate Cancer., PMID:31277465 • EDB-FN-targeted probes for near infrared fluorescent imaging and positron emission tomography imaging of breast cancer in mice., PMID:39333775 • Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade., PMID:35793468 • Evaluation of EDB Fibronectin in Plasma, Patient-Derived Xenograft Formalin-Fixed Paraffin-Embedded and Fresh Frozen Tumor Tissues Using Immunoaffinity LC-MS/MS., PMID:36049057 • EDB Fibronectin-Specific SPECT Probe ^99mTc-HYNIC-ZD2 for Breast Cancer Detection., PMID:30023665 • Tenascin-C: Form versus function., PMID:25482829 • EDB Fibronectin Specific Peptide for Prostate Cancer Targeting., PMID:25848940 • EDB fibronectin and angiogenesis -- a novel mechanistic pathway., PMID:16308732 • RT-PCR detection of fibronectin EDA+ and EDB+ mRNA isoforms: molecular markers for hepatocellular carcinoma., PMID:7509777
Nota	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Onfekafusp Alfa

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Datasheet

Anti-Human Fibronectin&TNF-alpha Reference Antibody (Onfekafusp Alfa, RUO).pdf

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Anti-Human Fibronectin&TNF-alpha Reference Antibody (Onfekafusp Alfa, RUO) (HP900016)

Vista general

Imágenes

Referencias

Datasheet

SDS