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Research Grade Orforglipron (SW328036)

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Vista general
Número de catálogoSW328036
Descripción
Research Grade Orforglipron (SW328036) is a rabbit polyclonal antibody detecting GLP-1 receptor in ELISA, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, Functional assay, Research in vivo
ClonalidadMonoclonal
IsotipoBiosynthetic GLP-1 analogs.
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Purified by HPLC.
Número de acceso P43220
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosLY3502970, OWL 833, OWL833, OWL-833
Fondo

Glucagon-like peptide 1 receptor (GLP-1 receptor,Glucagon-like peptide 1 receptor,GLP1R,GLP-1-R,GLP-1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722
2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095
3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125
4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449
5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895
6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285
7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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