Research Grade Orforglipron (SW328036)

Name: Research Grade Orforglipron
Brand: abinScience
SKU: SW328036
Price: 370 USD
Availability: InStock

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Numéro de catalogue	SW328036
Description	Research Grade Orforglipron (SW328036) is a rabbit polyclonal antibody detecting GLP-1 receptor in ELISA, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Human
Applications	ELISA, Functional assay, Research in vivo
Clonalité	Monoclonal
Isotype	Biosynthetic GLP-1 analogs.
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	GLP-1 receptor, Glucagon-like peptide 1 receptor, GLP1R, GLP-1-R, GLP-1R
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Purified by HPLC.
Numéro d'accès	P43220
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	LY3502970, OWL 833, OWL833, OWL-833
Contexte	Glucagon-like peptide 1 receptor (GLP-1 receptor,Glucagon-like peptide 1 receptor,GLP1R,GLP-1-R,GLP-1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. 1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722 2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095 3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125 4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449 5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895 6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285 7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712
Note	For research use only. Not suitable for clinical or therapeutic use.

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Research Grade Orforglipron (SW328036)

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