

| Каталожный номер | HV426016 |
|---|---|
| Описание |
Pintumomab (HV426016) is a research-grade recombinant antibody targeting DPEP3. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG1-kappa |
| Система экспрессии | Mammalian cells |
| Характер | Recombinant |
| Цель | DPEP3, Dipeptidase 3 |
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q9H4B8 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | 170, 339177-26-3 |
| Фон | Dipeptidase 3 (DPEP3) is a ~53 kDa protein. Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance. 1. Hayashi, K. et al. (2020) Journal of structural biology 211, 107512. PMID: 32325220 |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |

SDS-PAGE for Research Grade Pintumomab




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