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Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO) (JN072016)

Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO)
Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO)
Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO)
Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO)
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Aperçu
Numéro de catalogueJN072016
Description
Pritoxaximab (JN072016) is a research-grade recombinant antibody targeting shiga toxin type 1stx1B. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesEscherichia coli
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteChimeric
ClonalitéMonoclonal
IsotypeIgG1-kappa
Système d'expression Mammalian cells
Cible shiga toxin type 1stx1B
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q47641
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifsShigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx1, 1351470-16-0
Contexte

Shiga toxin subunit B (shiga toxin type 1Bstx1B) is a ~9 kDa protein. The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Pritoxaximab.

  • Anti-Escherichia coli shiga toxin type 1B/stx1B Reference Antibody (Pritoxaximab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Pritoxaximab

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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