Anti-Human CX3CL1/Fractalkine Reference Antibody (Quetmolimab, RUO) (HX143016)

Name: Anti-Human CX3CL1/Fractalkine Reference Antibody (Quetmolimab, RUO)
Brand: abinScience
SKU: HX143016
Price: 176 USD
Availability: InStock

データシート製品共有情報コピー

価格(USD):

スペック:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

数量:

お問い合わせ

概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HX143016
説明	Research Grade Quetmolimab (HX143016) is a humanized monoclonal antibody detecting Small-inducible cytokine D1 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG2-kappa
発現システム	Mammalian cells
種	Human
ターゲット	Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
エンドトキシンレベル	< 10 EU/mg
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P78423
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	E-6011, 2084037-83-0
背景	Fractalkine (Small-inducible cytokine D1,Fractalkine,Neurotactin,C-X3-C motif chemokine 1,NTT,CX3CL1,SCYD1,FKN,CX3C membrane-anchored chemokine) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. 1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230 2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356 3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118 5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005 6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663 7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350 8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Quetmolimab

参考文献

データシート

Anti-Human CX3CL1/Fractalkine Reference Antibody (Quetmolimab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human CX3CL1/Fractalkine Reference Antibody (Quetmolimab, RUO) (HX143016)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ