



| Número de catálogo | HT145016 |
|---|---|
| Descripción |
Quisovalimab (HT145016) is a research-grade recombinant antibody targeting CD258. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG4-kappa |
| Sistema de expresión | Mammalian cells |
| Objetivo | Herpes virus entry mediator ligand, LIGHT, CD258, HVEM-L, HVEML, TNFSF14, Tumor necrosis factor ligand superfamily member 14, Herpesvirus entry mediator ligand |
| Nivel de endotoxinas | < 10 EU/mg |
| Pureza | >95% purity as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | O43557 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | AEVI-002, CERC-002, F-19, MDGN-002, SAR-2520672427667-03-4 |
| Fondo | Tumor necrosis factor ligand superfamily member 14 (CD258/TNFSF14) is a ~26 kDa protein. Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production. 1. Tamada, K. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 4105-10. PMID: 10754304 2. Mauri, DN. et al. (1998) Immunity 8, 21-30. PMID: 9462508 |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107) |

SEC-HPLC detection for Research Grade Quisovalimab.

SDS-PAGE for Research Grade Quisovalimab.




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