Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO) (VK632066)

Name: Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO)
Brand: abinScience
SKU: VK632066
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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SDS

Vista general

Número de catálogo	VK632066
Descripción	Research Grade Rafivirumab (VK632066) is a canis monoclonal antibody detecting Glycoprotein in ELISA, FACS, Functional assay, Research in vivo. Suitable for Rabies virus (RABV). Highlights ●Multi-Application — Validated across multiple applications.
Reactividad de especies	Rabies virus (RABV)
Aplicaciones	ELISA, FACS, Functional assay, Research in vivo
Especie huésped	Canine
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
Aplicaciones probadas	WB
Objetivo	Glycoprotein, G
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O92284
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Glycoprotein (glycoprotein G) is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Rafivirumab
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein(Catalog No: VK632012)
Lane 2: negative control