Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO) (VK632066)

Name: Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO)
Brand: abinScience
SKU: VK632066
Price: 176 USD
Availability: InStock

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Numéro de catalogue	VK632066
Description	Research Grade Rafivirumab (VK632066) is a canis monoclonal antibody detecting Glycoprotein in ELISA, FACS, Functional assay, Research in vivo. Suitable for Rabies virus (RABV). Highlights ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Rabies virus (RABV)
Applications	ELISA, FACS, Functional assay, Research in vivo
Espèce hôte	Canine
Clonalité	Monoclonal
Isotype	IgG2a, kappa
Applications testées	WB
Cible	Glycoprotein, G
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	O92284
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Glycoprotein (glycoprotein G) is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Research Grade Rafivirumab
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein(Catalog No: VK632012)
Lane 2: negative control