Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO) (VK632066)

Name: Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO)
Brand: abinScience
SKU: VK632066
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер	VK632066
Описание	Research Grade Rafivirumab (VK632066) is a canis monoclonal antibody detecting Glycoprotein in ELISA, FACS, Functional assay, Research in vivo. Suitable for Rabies virus (RABV). Highlights ●Multi-Application — Validated across multiple applications.
Реактивность видов	Rabies virus (RABV)
Применения	ELISA, FACS, Functional assay, Research in vivo
Хозяинский вид	Canine
Клоональность	Monoclonal
Изотип	IgG2a, kappa
Проверенные приложения	WB
Цель	Glycoprotein, G
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	O92284
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Glycoprotein (glycoprotein G) is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Rafivirumab
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein(Catalog No: VK632012)
Lane 2: negative control