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Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO) (FF909026)

Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO)
Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO)
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  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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Vista general
Número de catálogoFF909026
Descripción
Research Grade Relfovetmab (FF909026) is a felinized monoclonal antibody detecting Nerve Growth Factor beta subunit in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Cat.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesFeline
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedFeline
ClonalidadMonoclonal
IsotipoIgG1-kappa
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo Beta-NGF, Beta-nerve growth factor, NGF, NGFB
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P01138
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosZTS-00084768, 2171034-70-9
FondoFrunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats.
• Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment., PMID:21358750
• Synthesis of the biologically active beta-subunit of human nerve growth factor in Escherichia coli., PMID:1537563
• Nerve growth factor translates stress response and subsequent murine abortion via adhesion molecule-dependent pathways., PMID:16371592
• Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes., PMID:2906326
• Nerve growth factor and the physiology of pain: lessons from congenital insensitivity to pain with anhidrosis., PMID:22882139
• A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception., PMID:14976160
• Rare human nerve growth factor-β mutation reveals relationship between C-afferent density and acute pain evaluation., PMID:27146986
• Linkage relationships of the gene for the beta subunit of nerve growth factor (NGFB) with other chromosome 1 marker loci., PMID:4006521
• Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen., PMID:23472850
• Assignment of the beta-nerve growth factor (NGFB) to bovine chromosome 3 band q23 by in situ hybridization., PMID:9284944
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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