Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO) (FF909026)

Name: Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO)
Brand: abinScience
SKU: FF909026
Price: 176 USD
Availability: InStock

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Numéro de catalogue	FF909026
Description	Research Grade Relfovetmab (FF909026) is a felinized monoclonal antibody detecting Nerve Growth Factor beta subunit in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Cat. Highlights ●Multi-Application — Validated across multiple applications.
Reactivité des espèces	Feline
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Feline
Clonalité	Monoclonal
Isotype	IgG1-kappa
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	Beta-NGF, Beta-nerve growth factor, NGF, NGFB
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P01138
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	ZTS-00084768, 2171034-70-9
Contexte	Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats. • Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment., PMID:21358750 • Synthesis of the biologically active beta-subunit of human nerve growth factor in Escherichia coli., PMID:1537563 • Nerve growth factor translates stress response and subsequent murine abortion via adhesion molecule-dependent pathways., PMID:16371592 • Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes., PMID:2906326 • Nerve growth factor and the physiology of pain: lessons from congenital insensitivity to pain with anhidrosis., PMID:22882139 • A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception., PMID:14976160 • Rare human nerve growth factor-β mutation reveals relationship between C-afferent density and acute pain evaluation., PMID:27146986 • Linkage relationships of the gene for the beta subunit of nerve growth factor (NGFB) with other chromosome 1 marker loci., PMID:4006521 • Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen., PMID:23472850 • Assignment of the beta-nerve growth factor (NGFB) to bovine chromosome 3 band q23 by in situ hybridization., PMID:9284944
Note	For research use only. Not suitable for clinical or therapeutic use.

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Anti-Human beta-NGF Reference Antibody (Relfovetmab, RUO) (FF909026)

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