







| Número de catálogo | HC669046 | ||||
|---|---|---|---|---|---|
| Descripción |
Rosopatamab (HC669046) is a research-grade recombinant antibody targeting NAALAD1. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB | ||||
| Especie huésped | Chimeric | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1-kappa | ||||
| Sistema de expresión | Mammalian cells | ||||
| Aplicaciones probadas | WB | ||||
| Objetivo | NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP | ||||
| Nivel de endotoxinas | < 10 EU/mg | ||||
| Pureza | >95% purity as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q04609 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Nombres alternativos | J-591, MLN-591, huJ-591, HuJ591-DOTA, Rosopatamabtetraxetan, 2260767-49-3 | ||||
| Fondo | Glutamate carboxypeptidase 2 (FOLH1/PSMA) is a ~84 kDa protein. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. | ||||
| Nota | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SEC-HPLC detection for Research Grade Rosopatamab.

Detects FOLH1/PSMA in indirect ELISAs.

SDS-PAGE for Anti-Human PSMA/FOLH1/NAALADase I Reference Antibody (Rosopatamab, RUO)

Western blot analysis was performed using anti-FOLH1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human FOLH1 (Catalog No: HC669021)
Lane 2: Negative control




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