Anti-Human FOLH1/PSMA Reference Antibody (Rosopatamab, RUO) (HC669046)

Name: Anti-Human FOLH1/PSMA Reference Antibody (Rosopatamab, RUO)
Brand: abinScience
SKU: HC669046
Price: 176 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC669046

Description

Rosopatamab (HC669046) is a research-grade recombinant antibody targeting NAALAD1. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactivité des espèces

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Espèce hôte

Chimeric

Clonalité

Monoclonal

Isotype

IgG1-kappa

Système d'expression

Mammalian cells

Applications testées

Cible

NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q04609

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

J-591, MLN-591, huJ-591, HuJ591-DOTA, Rosopatamabtetraxetan, 2260767-49-3

Contexte

Glutamate carboxypeptidase 2 (FOLH1/PSMA) is a ~84 kDa protein. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Rosopatamab.
Bioactivity

Detects FOLH1/PSMA in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human PSMA/FOLH1/NAALADase I Reference Antibody (Rosopatamab, RUO)
Western blot

Western blot analysis was performed using anti-FOLH1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human FOLH1 (Catalog No: HC669021)
Lane 2: Negative control