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| カタログ番号 | HC669046 | ||||
|---|---|---|---|---|---|
| 説明 |
Rosopatamab (HC669046) is a research-grade recombinant antibody targeting NAALAD1. Produced in mammalian cells with native-like glycosylation.
Highlights
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| 種反応性 | Human | ||||
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB | ||||
| 宿主種 | Chimeric | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1-kappa | ||||
| 発現システム | Mammalian cells | ||||
| テスト済みアプリケーション | WB | ||||
| ターゲット | NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% purity as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q04609 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 別名 | J-591, MLN-591, huJ-591, HuJ591-DOTA, Rosopatamabtetraxetan, 2260767-49-3 | ||||
| 背景 | Glutamate carboxypeptidase 2 (FOLH1/PSMA) is a ~84 kDa protein. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. | ||||
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SEC-HPLC detection for Research Grade Rosopatamab.
Detects FOLH1/PSMA in indirect ELISAs.
SDS-PAGE for Anti-Human PSMA/FOLH1/NAALADase I Reference Antibody (Rosopatamab, RUO)
Western blot analysis was performed using anti-FOLH1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human FOLH1 (Catalog No: HC669021)
Lane 2: Negative control
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