Anti-Human FOLH1/PSMA Reference Antibody (Rosopatamab, RUO) (HC669046)

Name: Anti-Human FOLH1/PSMA Reference Antibody (Rosopatamab, RUO)
Brand: abinScience
SKU: HC669046
Price: 176 USD
Availability: InStock

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Спецификация:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HC669046

Описание

Rosopatamab (HC669046) is a research-grade recombinant antibody targeting NAALAD1. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Реактивность видов

Human

Применения

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Хозяинский вид

Chimeric

Клоональность

Monoclonal

Изотип

IgG1-kappa

Система экспрессии

Mammalian cells

Проверенные приложения

Цель

NAALAD1, Prostate-specific membrane antigen, NAALADase I, PSMA, PSM, Pteroylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase 2, N-acetylated-alpha-linked acidic dipeptidase I, Glutamate carboxypeptidase II, FOLH1, FGCP, FOLH, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, GCPII, Membrane glutamate carboxypeptidase, Cell growth-inhibiting gene 27 protein, mGCP

Уровень эндотоксинов

< 10 EU/mg

Чистота

>95% purity as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q04609

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

J-591, MLN-591, huJ-591, HuJ591-DOTA, Rosopatamabtetraxetan, 2260767-49-3

Фон

Glutamate carboxypeptidase 2 (FOLH1/PSMA) is a ~84 kDa protein. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.

Примечание

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

SEC-HPLC

SEC-HPLC detection for Research Grade Rosopatamab.
Bioactivity

Detects FOLH1/PSMA in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human PSMA/FOLH1/NAALADase I Reference Antibody (Rosopatamab, RUO)
Western blot

Western blot analysis was performed using anti-FOLH1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human FOLH1 (Catalog No: HC669021)
Lane 2: Negative control