Anti-Human CD4 Reference Antibody (Semzuvolimab, RUO) (HF998086)

Name: Anti-Human CD4 Reference Antibody (Semzuvolimab, RUO)
Brand: abinScience
SKU: HF998086
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF998086

Description

Semzuvolimab (HF998086) is a research-grade recombinant antibody targeting CD4. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Reactivité des espèces

Human

Applications

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

Espèce hôte

Chimeric

Clonalité

Monoclonal

Isotype

IgG1-kappa

Applications testées

Cible

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P01730

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

UB421, UB-421, UB421, 2409099-32-5

Contexte

T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SDS-PAGE

SDS-PAGE for Research Grade Semzuvolimab.
Bioactivity

Detects recombinant CD4 (Catalog No: HF998011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998011)
Lane 2: Negative control
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998012)
Lane 2: Negative control