Anti-Human CD4 Reference Antibody (Semzuvolimab, RUO) (HF998086)

Name: Anti-Human CD4 Reference Antibody (Semzuvolimab, RUO)
Brand: abinScience
SKU: HF998086
Price: 176 USD
Availability: InStock

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100ug
1mg
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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HF998086

説明

Semzuvolimab (HF998086) is a research-grade recombinant antibody targeting CD4. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

種反応性

Human

アプリケーション

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

宿主種

Chimeric

クローン性

Monoclonal

アイソタイプ

IgG1-kappa

テスト済みアプリケーション

ターゲット

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

エンドトキシンレベル

< 10 EU/mg

純度

>95% as determined by SDS-PAGE.

精製

Protein A/G purified from cell culture supernatant.

アクセッション番号

P01730

形態

Liquid

保存バッファー

0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

別名

UB421, UB-421, UB421, 2409099-32-5

背景

T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

注意事項

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Semzuvolimab.
Bioactivity

Detects recombinant CD4 (Catalog No: HF998011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998011)
Lane 2: Negative control
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998012)
Lane 2: Negative control