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Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO) (JN822016)

Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)
Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)
Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)
Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерJN822016
Описание
Setoxaximab (JN822016) is a research-grade recombinant antibody targeting shiga toxin type 2stx2A. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовEscherichia coli
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видChimeric
КлоональностьMonoclonal
ИзотипIgG1-kappa
Система экспрессии Mammalian cells
Цель shiga toxin type 2stx2A
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P09385
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияShigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx2, 1351470-17-1
Фон

Shiga-like toxin 2 subunit A (shiga toxin type 2Astx2A) is a ~35 kDa protein. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.

Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Setoxaximab.

  • Anti-Escherichia coli shiga toxin type 2A/stx2A Reference Antibody (Setoxaximab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Setoxaximab

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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