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Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO) (HC359056)

Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Precio(USD):
Especificación:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Número:
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  • Vista general

  • Imágenes

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  • Datasheet

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Vista general
Número de catálogoHC359056
Descripción
Simridarlimab (HC359056) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB
Especie huéspedHuman
ClonalidadMonoclonal
Isotipo(G1_L-kappa)_VH-VH-h-CH2-CH3
Aplicaciones probadas WB
Objetivo B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, Antigenic surface determinant protein OA3, CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9NZQ7 & Q08722
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosBispecific, IBI322, IBI-322, IBI3222378862-90-7
FondoSimridarlimab is a humanized IG antibody targeting CD274/CD47.
Nota For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Imágenes
  • Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Simridarlimab.

  • Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

    Bioactivity

    Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.

  • Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

    Western blot

    Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human PDL1 (Catalog No: HV974011)
    Lane 2: Negative control

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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