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Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO) (HC359056)

Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)
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  • 概要

  • イメージ

  • 参考文献

  • データシート

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概要
カタログ番号HC359056
説明
Simridarlimab (HC359056) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB
宿主種Human
クローン性Monoclonal
アイソタイプ(G1_L-kappa)_VH-VH-h-CH2-CH3
テスト済みアプリケーション WB
ターゲット B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, Antigenic surface determinant protein OA3, CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q9NZQ7 & Q08722
形態 Liquid
保存バッファー 0.01M PBS pH 7.4.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Bispecific, IBI322, IBI-322, IBI3222378862-90-7
背景Simridarlimab is a humanized IG antibody targeting CD274/CD47.
注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
イメージ
  • Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Simridarlimab.

  • Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

    Bioactivity

    Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.

  • Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

    Western blot

    Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human PDL1 (Catalog No: HV974011)
    Lane 2: Negative control

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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