

| Número de catálogo | HY428026 |
|---|---|
| Descripción |
Sotatercept (HY428026) is a research-grade recombinant antibody targeting EDF. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Functional assay, Research in vivo |
| Clonalidad | Monoclonal |
| Isotipo | Fusion - [ACVR2A (activin A receptor type 2A, ActR-II, ActRIIA)]2 - IGHG1 Fc (Fragment constant) |
| Sistema de expresión | Mammalian cells |
| Naturaleza | Recombinant |
| Objetivo | EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain |
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P08476 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7 |
| Fondo | Inhibin beta A chain (INHBA) is a ~47 kDa protein. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Sotatercept




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