

| Numéro de catalogue | HY428026 |
|---|---|
| Description |
Sotatercept (HY428026) is a research-grade recombinant antibody targeting EDF. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactivité des espèces | Human |
| Applications | ELISA, Functional assay, Research in vivo |
| Clonalité | Monoclonal |
| Isotype | Fusion - [ACVR2A (activin A receptor type 2A, ActR-II, ActRIIA)]2 - IGHG1 Fc (Fragment constant) |
| Système d'expression | Mammalian cells |
| Nature | Recombinant |
| Cible | EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain |
| Niveau d'endotoxines | < 10 EU/mg as determined by LAL method. |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P08476 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7 |
| Contexte | Inhibin beta A chain (INHBA) is a ~47 kDa protein. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Sotatercept




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