Anti-Human Clusterin Reference Antibody (Sotevtamab, RUO) (HY453016)

Name: Anti-Human Clusterin Reference Antibody (Sotevtamab, RUO)
Brand: abinScience
SKU: HY453016
Price: 176 USD
Availability: InStock

データシート製品共有情報コピー

価格(USD): --

スペック:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

数量:

お問い合わせ

概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HY453016
説明	Sotevtamab (HY453016) is a research-grade recombinant antibody targeting APOJ. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG2-kappa
発現システム	Mammalian cells
性質	Recombinant
ターゲット	APOJ, ApoJalpha, NA1/NA2, Complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Ku70-binding protein 1, Testosterone-repressed prostate message 2, ApoJbeta, TRPM-2, Complement cytolysis inhibitor b chain, SGP-2, KUB1, Apolipoprotein J, Apo-J, Clusterin, Sulfated glycoprotein 2, Aging-associated gene 4 protein, CLI, CLU, Complement-associated protein SP-40, 40
エンドトキシンレベル	< 10 EU/mg as determined by LAL method.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P10909
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	16B5, AB-16B52411526-47-9
背景	Clusterin (APOJ/SP-40) is a ~52 kDa protein. Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. 1. Poon, S. et al. (2000) Biochemistry 39, 15953-60. PMID: 11123922 2. Wyatt, AR. et al. (2009) The Journal of biological chemistry 284, 21920-21927. PMID: 19535339 3. Poon, S. et al. (2002) The Journal of biological chemistry 277, 39532-40. PMID: 12176985 4. Stewart, EM. et al. (2007) Biochemistry 46, 1412-22. PMID: 17260971 5. Wyatt, AR. et al. (2010) The Journal of biological chemistry 285, 3532-3539. PMID: 19996109 6. Hatters, DM. et al. (2002) European journal of biochemistry 269, 2789-94. PMID: 12047389 7. Kumita, JR. et al. (2007) Journal of molecular biology 369, 157-67. PMID: 17407782 8. Yerbury, JJ. et al. (2007) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21, 2312-22. PMID: 17412999
注意事項	For research use only. Not suitable for clinical or therapeutic use.

イメージ

SDS-PAGE

SDS-PAGE for Research Grade Sotevtamab

参考文献

データシート

Anti-Human Clusterin Reference Antibody (Sotevtamab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human Clusterin Reference Antibody (Sotevtamab, RUO) (HY453016)

概要

イメージ

参考文献

データシート

SDS